Novel First-in-Class Drug Promising in Early ADHD Study

Medscape

A novel orexin-2 receptor agonist, ALKS 7290, showed clinically meaningful improvements in ADHD symptoms in a phase 1B study, with significant reductions in severity scores observed as early as day 6. Both 20-mg and 50-mg doses were well tolerated, with no serious adverse events. This marks the first clinical evidence of orexin receptor agonists' potential in treating ADHD.

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All articles from 23 September 2026. Summaries are AI-generated and may contain errors; the linked article is the authority.